Here are some good reasons to choose Big Fat Spark together with 123ignition when operating multi cylinder engines.
123ignition (in general) needs a certain, for high-performance ignition modules relatively high, resistance in the primary windings of the coil. The high resistance limits the electrical current flow to a degree the 123ignition can handle. If the resistance is too low (and therefore the electrical current flow too high), the electronics of the 123ignition either cuts off the current flow (protective circuit) or, in case the current is only slightly too high, the 123ignition will behave strangely giving non-consistent ignition values (ignition timing bouncing around 10-15 degrees).
Coils with relatively high resistance, used to counteract this sort of problem, have the big disadvantage of having a relatively long charge time. Engines with 4 cylinders revving in a normal range normally do not experience problems however engines with more cylinders or engines using higher revs may experience problems.